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Severe early-onset obesity-insulin resistance syndrome due to SH2B1 deficiency
1 associated gene
No signs/symptoms info
PROTEIN INTERACTIONS: 1
Hereditary breast cancer
6 OMIM references -
4 associated genes
No signs/symptoms info
Severe early-onset obesity-insulin resistance syndrome due to SH2B1 deficiency
Hereditary breast cancer

SH2B1
(UniProt - OMIM)
 BRCA1
(UniProt - OMIM)
BRCA2
(UniProt - OMIM)
KLLN
(UniProt - OMIM)
XRCC2
(UniProt - OMIM)

INTERACTOME
ASSOCIATIONS
(click on a score value to see the evidence)
SH2B1
(0.63)
BRCA1


Citations in the biomedical literature:


Severe early-onset obesity-insulin resistance syndrome due to SH2B1 deficiency
SH2B1
Hereditary breast cancer
BRCA1 BRCA2 KLLN XRCC2



Severe early-onset obesity-insulin resistance syndrome due to SH2B1 deficiency
Hereditary breast cancer

Synonym(s):
(no synonyms)

Synonym(s):
- Familial breast cancer
- Familial breast carcinoma
- Hereditary breast carcinoma
Classification (Orphanet):
- Rare endocrine disease
- Rare genetic disease
Classification (Orphanet):
- Rare genetic disease
- Rare gynecologic or obstetric disease
- Rare oncologic disease
Classification (ICD10):
- Endocrine, nutritional and metabolic diseases -
Classification (ICD10):
- Neoplasms -
Epidemiological data:
Class of prevalence: <1 / 1 000 000
Average age onset: childhood
Average age of death: -
Type of inheritance: autosomal dominant
Epidemiological data:
(no data available)
External references:
No OMIM references
No MeSH references
External references:
6 OMIM references -
No MeSH references
No signs/symptoms info available.